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王 超 教授 理學(xué)博士

辦公電話：010-82805049

電子信箱：chaowang@bjmu.edu.cn

研究方向：藥物化學(xué)，多肽化學(xué)

1961年4月出生。1995年于北京醫(yī)科大學(xué)藥學(xué)院獲理學(xué)博士學(xué)位。2003年晉升為教授。碩士生導(dǎo)師。2001、－2002年在法國國家科研中心的"結(jié)構(gòu)生物學(xué)研究所"和"氨基酸、多肽、蛋白質(zhì)實驗室"做博士后。曾在基于甾體和多肽相互作用的先導(dǎo)結(jié)構(gòu)研究和基于糖胺的先導(dǎo)結(jié)構(gòu)研究兩個方向展開基礎(chǔ)和應(yīng)用基礎(chǔ)研究。獲得了10項國家和省部級科技進(jìn)步獎。申請了多項發(fā)明專利。

現(xiàn)教授本科生課程："藥物的波譜解析"。

代表性學(xué)術(shù)論文:

1.Ying Yang, Chao Wang*, Synthesis of functional amino acids bearing 1,3-dithiane modification, Journal of Chinese Pharmaceutical Sciences, 2011, 20(2): 195-198.

2.Wei-wei Wang, Ting Yu, Chao Wang*, Synthesis of a novel conformational restricted amino acid for potential use in peptide chemistry, Heterocyclic Communications, 2009, 15(6).

3. Yong Sun, Xiang-Qin Li, Yun-Ping Meng, Chao Wang*, Synthesis of the Protected Dithiols Amino Acids for Potential Use in Peptide Chemistry, Synthetic Communication, 2008, 38: 3303-3310.

4.Keli Gu, Lanrong Bi, Ming Zhao, Chao Wang, Cheryl Dolan, Michael C. Kao, Jeffrey B.-H. Tok and Shiqi Peng*, Stereoselective synthesis and anti-inflammatory activities of 6- and 7-membered dioxacycloalkanes. Bioorg. & Med. Chem. 2006, 14:1339-1347.

5. Chao Wang, Ming Zhao, Xuecai Qiu, Shiqi Peng, The synthesis and immunosuppressive activities of steroid-urotoxin linkers. Bioorg. & Med. Chem. 2004, 12: 4403-4421.

6.Chao Wang, Ming Zhao, Jian Yang, Xingwei Li,Shiqi Peng，Synthesis and evaluations of pentahydroxylhexyl-L-cysteine and its dimmer as chelating agents for cadmium or lead decorporation. Toxicology and Applied Pharmacology 200, 2004, 229-236.

7.Chao Wang, Wenfeng Ding, Ming Zhao, Shiqi Peng*, Studies on the Large Scale Synthesis and Anti-tumor Activity of YSL, Preparative Biochemistry & Biotechnology, 2003, 33(3), 189-196.

8.Chao Wang, Weina Cui, Ming Zhao, Jian Yang and Shiqi Peng*, Studies on the Synthesis and anti-Osteoporosis of Estrogen-GHRPS Linkers, Bioorganic & Medicinal Chemistry Letters, 2003, 13, 143-146.

9.Chao Wang, Ming Zhao, Weina Cui, Jian Yang and Shiqi Peng*, Studies on  the Synthesis of Estrogen- GHRPS Linkers, Synthetic Communications, 2003, 33(10), 1633-1641.

10.Chao Wang, Ming Zhao, Jian Yang, Shiqi Peng*, Synthesis and analgesic effects of kyotorphin-steroid linkers, Steroids, 2001, 66, 811-815.

11.Chao Wang, Yiou Fang, and Shiqi Peng*, Synthesis of Novel Chelating Agents and Their Effect on Cadmium Decorporation, Chem. Res.Toxicol. 1999, 12, 331-334.